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Horses can also get very serious 'travel sickness' if they are unable to lower their heads to clear their throat from time to time, such as in a trailer. I've also heard of some horses that refuse to urinate in a trailer, because it splashes on theire legs or is wet under their hooves. Most people would stop to let the horse stretch their legs every couple of hours.
Especially for races, because if the horse does come down with travel sickness they will get very sick, unless they're dosed with penicillin, which means they return a positive drug swab and are disqualified.
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